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  April 2015
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RNA-Seq
RNA-Seq (Transcriptome) is used for transcriptome quantification and structural analysis. The transcriptome analysis lays the foundation for gene structure and function research. RNA-Seq delivers unbiased transcriptome information for basic and medical research, pharmacogenomics research, and drug discovery and development.
Whole Genome Resequencing
The ability of NGS to sequence the whole genome has enabled large-scale comparative studies to be performed in an effort to understand how genetic differences affect health and diseases. BGI uses state-of-the art sequencing and bioinformatics technology to achieve a comprehensive analysis of genomic variations.
Target Region Sequencing
Target region capture enriches specific regions (e.g., the MHC region) or specific genes by probe hybridization based on probes designed according to the genomic regions of interest. It is cost effective to use targeted region sequencing to find variants with large samples.
Analysis of Transcriptome Differences between Resistant and Susceptible Strains of the Citrus Red Mite Panonychus citri (Acari: Tetranychidae).
Plos One. DOI: 10.1371. (2011).
The citrus red mite is a worldwide citrus pest and a common sensitizing allergen of asthma and rhinitis. It has developed strong resistance to many registered acaricides, However, the molecular mechanisms of resistance remain unknown. In this study, a comparative transcriptome study was carried out in the susceptible strain (SS) and resistant strain of the Citrus red mite to study mite resistance. 2,701 differentially expressed genes (DEGs) based on the uniquely mapped reads were identified by the comparing the differences between RS and SS. Moreover, we identified 211 metabolism genes and target genes related to general insecticide resistance such as P450 and Cytochrome b, and further compared their differences between RS and SS.
Ancient human genome sequence of an extinct Palaeo-Eskimo
Nature 2010; 463: 757-762.
In 2010, BGI and Copenhagen University obtained DNA from a 4,000-year-old permafrost-preserved human hair, and isolated and sequenced its genomic DNA. The genome is from a male individual who was a member of the first known population to settle in Greenland. SNP analysis of the sequence data enabled the researchers to assign possible phenotypic characteristics of this individual and identify the population to which he is most closely related. This analysis provided evidence that there was human migration from Siberia into the New World about 5,500 years ago, and this migration was independent of the one that gave rise to the modern Native Americans and Inuits.
 
Latest Study Finds BGI’s NIFTY® Test Performs Best in Noninvasive Prenatal Screening
Chinese researchers completed genome sequencing of the Perciform Fish Larimichthys crocea
BGI Approved to Conduct High-throughput Clinical Genetic Sequencing Services on Cancer Diagnosis and Treatment in China
  China’s Genome-Mapping Giant BGI Is Poised to Become an International Leader in Gene Sequencing and May Play Major Role in Interpretation of Genetic Test Results-DARK Daily
Plant Genomics Congress UK 5.11-12 London
cfDNA 2015 5.28-29 Copenhagen
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